Reduced functional connectivity in the prefrontal cortex of elderly catatonia patients: A longitudinal study using functional near-infrared spectroscopy

Catatonia is a syndrome that manifests in patients with mental disorders and general medical conditions. However, functional changes to the brain cause catatonia remain unknown. In present study, we used near-infrared spectroscopy (fNIRS) assess spontaneous hemodynamic activities at times of onset resolution catatonic symptoms catatonia. We 22-channel 49-channel fNIRS examine prefrontal cortex (PFC), both frontal parietal cortices, respectively. A total ten who were diagnosed included study. Resting state measurements taken for five minutes time symptoms. Analyses performed region motor within parietal-frontal brain. Functional connectivity between cerebral hemispheres was evaluated systematically based on oscillation ?[HbO2]. PFC, resting (RSFC) significantly lower than eyes-closed non-catatonic (p = 0.047). The study demonstrated RSFC measured using fNIRS, may be an objective indicator change